Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Special Drug Use-results Surveillance of Tafinlar/Mekinist

 		BRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid Tumor Japan NCT06262919

A Post Approval Commitment Study on Tabrecta® (Capmatinib) in South Korea

 		Non-Small-Cell Lung Carcinoma Korea, Republic of NCT05703516

Specified Drug-use Survey of Leqvio for s.c. Injection.

 		Familial Hypercholesterolaemia, Hypercholesterolaemia Japan NCT06275724

Roll-over Study to Allow Continued Access to Ribociclib

 		Metastatic Breast Cancer Phase4 Argentina
Brazil
Costa Rica
Peru
United States
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 NCT05161195

Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment

 		Advanced Breast Cancer Phase4 India NCT05631795

Open-label, Long-term Safety Study of Secukinumab in Polymyalgia Rheumatica (PMR)

 		Polymyalgia Rheumatica Phase3 Argentina
Australia
Germany
Japan
Spain
Switzerland
United States
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 NCT06331312

A Global Study of Midostaurin in Combination With Chemotherapy to Evaluate Safety, Efficacy and Pharmacokinetics in Newly Diagnosed Pediatric Patients With FLT3 Mutated AML

 		FLT3-mutated Acute Myeloid Leukemia Phase2 Austria
Czechia
Germany
Italy
Jordan
Korea, Republic of
Poland
Slovenia
Turkey
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 NCT03591510

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

 		Solid Tumor Phase1, Phase2 United States NCT04939610

Study Assessing the Efficacy and Safety of a Personalized Monotherapy Regimen of Brolucizumab in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy

 		Macular Polypoidal Choroidal Vasculopathy (PCV) Phase3 Korea, Republic of NCT05666804

Revolade Tablets Specified Drug-use Survey

 		Aplastic Anemia Japan NCT06287268