Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location NCT ID

Study of Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of NIO752 in Early Alzheimer's Disease Participants

 		Alzheimer Disease, Mild Cognitive Impairment Phase1 France
Spain 		NCT05469360

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

 		Prostate Cancer Phase3 Australia
Brazil
China
Hong Kong
India
Japan
Singapore
South Korea
Taiwan
United Kingdom
United States
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 NCT06855277

Phase IIIb Study of Ribociclib + ET in Early Breast Cancer

 		Early Breast Cancer Phase3 Australia
Canada
China
Germany
Hong Kong
India
Israel
Mexico
Portugal
Puerto Rico
South Korea
Taiwan
Turkey (Türkiye)
United States
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 NCT05827081

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

 		Metastatic Hormone-sensitive Prostate Cancer Phase2 Australia
Canada
China
Czechia
France
Germany
Italy
Netherlands
Poland
Singapore
South Korea
Spain
Taiwan
United States
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 NCT06991556

Ofatumumab in Portuguese Multiple Sclerosis Patients - an Observational Study

 		Relapsing Multiple Sclerosis Portugal NCT05809986

Long-Term Safety of Lutetium (177Lu) Vipivotide Tetraxetan in Participants With Prostate Cancer

 		Prostate Cancer Phase4 Austria
Belgium
Canada
Czechia
France
Germany
Netherlands
Spain
Sweden
United Kingdom
United States
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 NCT05803941

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

 		HR+/HER2- Early Breast Cancer Saudi Arabia NCT06797531

Inclisiran (Leqvio®) in Patients With Atherosclerotic Vascular Disease and/or Heterozygous Familial Hypercholesterolemia Treated in Spain: the INSPIRE Study

 		Atherosclerotic Vascular Disease, Heterozygous Familial Hypercholesterolemia Spain NCT06958315

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

 		Sickle Cell Disease Phase1, Phase2 United States NCT06546670

Concentration of Ofatumumab in the Breast Milk of Lactating Women With Relapsing Forms of Multiple Sclerosis

 		Multiple Sclerosis Phase4 Germany
Puerto Rico
United Kingdom
United States
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 NCT06444113