Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

 		Systemic Lupus Erythematosus Phase3 Brazil
Bulgaria
Canada
China
Czechia
Guatemala
Hungary
Israel
Japan
Poland
Portugal
Singapore
Slovakia
South Africa
Spain
Thailand
Turkey
United States
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 NCT05639114

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

 		Aortic Stenosis Phase2 Austria
Canada
Czechia
Denmark
France
Germany
Israel
Italy
Portugal
Spain
Switzerland
United Kingdom
United States
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 NCT05646381

A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.

 		Breast Cancer Phase1, Phase2 Australia
Canada
China
France
Korea, Republic of
Singapore
Spain
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 NCT06247995

Efficacy and Safety of Remibrutinib Compared to Teriflunomide in Participants With Relapsing Multiple Sclerosis (RMS)

 		Relapsing Multiple Sclerosis Phase3 Argentina
Brazil
Bulgaria
Canada
China
Croatia
Estonia
France
Greece
India
Italy
Japan
Mexico
Poland
Portugal
Puerto Rico
Romania
Slovakia
Slovenia
South Africa
Spain
Sweden
Turkey
United Kingdom
United States
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 NCT05156281

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

 		Relapsing Multiple Sclerosis Phase3 United States NCT03650114

Coronary Computed Tomography Study to Assess the Effect of Inclisiran in Addition to Maximally Tolerated Statin Therapy on Atherosclerotic Plaque Progression in Participants With a Diagnosis of Non-obstructive Coronary Artery Disease Without Previous Cardiovascular Events

 		Coronary Artery Disease Phase3 Argentina
Australia
Belgium
Brazil
Canada
Chile
China
France
Hungary
India
Ireland
Italy
Japan
Korea, Republic of
Spain
Switzerland
United Kingdom
United States
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 NCT05360446

Ribociclib Real-world Treatment Patterns and Clinical Outcomes Among Women With HR+/HER2- Advanced or Metastatic Breast Cancer in France

 		Breast Cancer France NCT05697146

Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

 		Neovascular Age-related Macular Degeneration United Arab Emirates NCT05266495

A Study to Investigate the Safety, Tolerability and Preliminary Efficacy of NGI226 Microparticles in Patients With Achilles Tendinopathy

 		Achilles Tendinopathy Phase2 France
Germany
United Kingdom
United States
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 NCT05592990

A Study of BION-1301 in Adults With IgA Nephropathy

 		IgA Nephropathy, Immunoglobulin A Nephropathy Phase3 Argentina
Australia
Belgium
Brazil
Canada
China
Croatia
Czechia
France
Germany
Greece
India
Israel
Italy
Japan
Korea, Republic of
Malaysia
Mexico
Spain
Taiwan
Turkey
United Kingdom
United States
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 NCT05852938