Active Clinical Trials
Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.
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Study title
Condition
Phase
Location
NCT ID
Study title
Condition
Phase
Location
NCT ID
Phase I Study of [177Lu]Lu-DFC413 in Patients With Solid Tumors
Pancreatic Ductal Adenocarcinoma, Non-Small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer, Triple Negative Breast Cancer, Colorectal Cancer, Soft Tissue Sarcoma
Phase1
Canada France IsraelSingapore
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NCT07261631
Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of OJR520 in Healthy Volunteers and Participants With Chronic Kidney Disease
Chronic Kidney Disease
Phase1
Germany United States
NCT07235059
A Phase Ib/II Open-label Study of AMO959 With Lutetium (177Lu) Vipivotide Tetraxetan (AAA617) in Combination With ARPI in Adult Participants With PSMA-positive mCRPC
PSMA-positive Metastatic Castration Resistant Prostate Cancer (mCRPC) With Prior Exposure to One Prior ARPI Who Are Candidates for Taxane-based Chemotherapy
Phase1, Phase2
Australia France JapanSpain United States
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NCT07226986
A Study to Investigate the Efficacy, Safety, Tolerability and Pharmacokinetics of PKN605 in Participants With Atrial Fibrillation
Atrial Fibrillation
Phase2
Canada China GermanyNetherlands Singapore United Kingdom United States
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NCT07217067
Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
Phase2
Bulgaria Canada CzechiaFrance Germany Malaysia Poland Singapore United States
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NCT07220577
A Phase II Trial to Evaluate the Clinical Efficacy, Safety and Tolerability of MAS825 in Pediatric and Adult Participants With Still's Disease
Still´s Disease
Phase2
Canada France GermanyItaly Netherlands Spain Turkey (Türkiye) United States
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NCT07203001
A Phase I/II, Dose Finding and Optimization Study of [177Lu]Lu-NeoB in Combination With Capecitabine in Patients With GRPR+, ER+, HER2- Metastatic Breast Cancer After Progression on Previous Endocrine Therapy in Combination With a CDK4/6 Inhibitor.
Breast Cancer
Phase1, Phase2
Australia Canada ChinaFrance Germany Italy Netherlands Portugal Singapore South Korea Spain United Kingdom United States
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NCT06247995
Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS)
Progressive Multiple Sclerosis
Phase1, Phase2
Australia Canada FranceGermany Italy Spain Switzerland
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NCT06675864
A Long-term Safety Study in Brazilian Patients With a Diagnosis of Spinal Muscular Atrophy Treated With Zolgensma
Spinal Muscular Atrophies
Brazil
NCT06019637
24 Weeks Double-blind Randomized Placebo-controlled Trial to Evaluate Efficacy, PK, Safety of LOU064 in Adolescents (12 - <18) With CSU and Inadequate Response to H1-antihistamine Followed by Optional 3 Years Open-label Extension and an Optional 3 Years Safety Long-term Treatment-free Follow-up
Chronic Spontaneous Urticaria
Phase3
Argentina Canada ChinaGermany Hong Kong Italy Japan Malaysia Netherlands Poland Singapore South Africa Spain Thailand Turkey (Türkiye) United Kingdom United States
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NCT05677451
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