Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

RWE Non-Interventional Prospective Study of Ribociclib Effectiveness and Safety in Patients With HR+/HER2- Early Breast Cancer in Saudi Arabia

 		HR+/HER2- Early Breast Cancer Saudi Arabia NCT06797531

A Study to Investigate the Pharmacokinetics and Safety of Remibrutinib in Participants With Severe Renal Impairment Compared to Matched Healthy Participants.

 		Autoimmune and Chronic Inflammatory Diseases Phase1 United States NCT07032272

NIS PDC the Efficacy and Safety of Iptacopan in Adults in Routine Clinical Practice

 		Paroxysmal Nocturnal Hemoglobinuria Russia NCT07036718

Efficacy and Safety of Remibrutinib After Switching From Ocrelizumab in Participants Living With Relapsing Multiple Sclerosis.

 		Relapsing Multiple Sclerosis Phase3 Australia
Canada
South Africa 		NCT06846281

Pelacarsen Roll-over Extension Program

 		Atherosclerotic Cardiovascular Disease Phase3 United States NCT06875973

Long-term Follow up Local Registry Study of Kymriah in South Korea

 		B-Cell Acute Lymphoblastic Leukemia, Diffuse Large B-Cell Lymphoma, Follicular Lymphoma South Korea NCT06785818

Inclisiran Effectiveness in China: a Pragmatic Randomized Trial

 		Coronary Heart Disease Phase4 China NCT06941792

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

 		Kidney Diseases, Kidney Diseases, Chronic, Urological Diseases, Glomerulonephritis, Glomerular Disease, Glomerulonephritis, IGA, Glomerulopathy, Immunoglobulin Disease Phase3 United States NCT06858319

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

 		Prostate Cancer Phase3 Australia
China
Japan
Singapore
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 NCT06855277

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

 		Glomerulonephritis, IGA, Immunoglobulin A Nephropathy Phase2 Malaysia
United States 		NCT06797518