Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Registry of Patients With a Diagnosis of Spinal Muscular Atrophy (SMA)

 		Spinal Muscular Atrophy (SMA) Greece
Ireland
Israel
Korea, Republic of
Poland
Portugal
Romania
Russian Federation
Taiwan
United States
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 NCT04174157

Secukinumab Drug Survival, Effectiveness and Tolerability in Pediatric Patients With Psoriasis

 		Moderate-to-severe Plaque Psoriasis Russian Federation NCT06142357

Study to Allow Patients Previously Participating in a Novartis Sponsored Trial to Continue Receiving Capmatinib Treatment as Single Agent or in Combination With Other Treatments or the Combination Treatment Alone

 		Advanced Solid Tumors Which Are cMET-dependent Phase2 Germany
Korea, Republic of
Singapore
United States
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 NCT03040973

Lp(a) Lowering Study of Pelacarsen (TQJ230) in US Black/African American and Hispanic Participants With Elevated Lp(a) and Established ASCVD

 		Elevated Lp(a) and Established Atherosclerotic Cardiovascular Disease Phase3 United States NCT06267560

Clinical Study To Further Evaluate The Efficacy Of Dabrafenib Plus Trametinib In Patients With Rare BRAF V600E Mutation-Positive Unresectable or Metastatic Solid Tumors

 		Rare Unresectable or Metastatic BRAF V600E Mutation-positive Solid Tumors United States NCT05868629

Kesimpta (Ofatumumab) Pregnancy Registry

 		Multiple Sclerosis, Pregnancy United States NCT05634967

A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 for Inflammatory Marker Reduction in Adult Participants With Coronary Heart Disease and Elevated hsCRP

 		Coronary Heart Disease Phase2 United States NCT06031844

Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy

 		Atypical Hemolytic Uremic Syndrome Phase3 Austria
Brazil
China
Czechia
Greece
India
Japan
Korea, Republic of
Slovakia
Slovenia
Taiwan
United Kingdom
United States
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 NCT04889430

Study of Safety, Tolerability and Clinical Outcomes of Egaten in Fascioliasis Patients (6 Years of Age or Older).

 		Fascioliasis Phase4 Colombia
Egypt
Peru
Vietnam
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 NCT04230148

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

 		Plaque, Atherosclerotic Phase4 China NCT06372925