Last Update: Feb 03, 2026
A Prospective Study to Describe the Real-world Treatment Outcomes in Canadian Patients With Moderate-to-severe Hidradenitis Suppurativa Treated With secukInumab (HS-RISE)
ClinicalTrials.gov Identifier:
Novartis Reference Number:CAIN457MCA01
All compounds are either investigational or being studied for (a) new use(s). Efficacy and safety have not been established. There is no guarantee that they will become commercially available for the use(s) under investigation.

Study Description

The HS-RISE study aims to assess real-world HS treatment outcomes and patterns, safety of secukinumab, and to describe the baseline characteristics of patients diagnosed with moderate-to- severe HS who are prescribed secukinumab in Canadian routine clinical practice.

Hidradenitis Suppurativa
Recruiting
142
Dec 12, 2025
Jan 15, 2028
All
18 Years - 100 Years (Adult, Older Adult)

Eligibility Criteria

Inclusion Criteria:

1. Patients must give written, signed, and dated informed consent before any information is collected and any study-related activity is performed.
2. Adult patients at the time of informed consent signature.
3. Patients with the diagnosis of moderate-to-severe HS, as determined by the dermatologist.
4. Patients who have been newly prescribed secukinumab as part of routine clinical care according to the approved Canadian PM. The decision to prescribe secukinumab must be made prior to,and independent of, study participation. First treatment with secukinumab must occur no more than 7 days (≤7 days) prior to Baseline visit.
5. Patients who can understand written and spoken Canadian English or French.

Exclusion Criteria:

1. Any medical or psychological condition in the treating physician's opinion that may prevent the patient from study participation.
2. Patients who have any contraindications to treatment with secukinumab, as defined in the Canadian PM.
3. Patients who have had any prior exposure to secukinumab (i.e., \>7 days prior to the baseline visit).

Novartis Investigative Site

Recruiting

Winnipeg,Manitoba,R3m 3z4,Canada

Novartis Investigative Site

Recruiting

Hamilton,Ontario,L8p4b4,Canada

Novartis Investigative Site

Recruiting

Markham,Ontario,L3p 1x3,Canada

Novartis Investigative Site

Recruiting

Mississauga,Ontario,L4w 0c2,Canada

Novartis Investigative Site

Recruiting

Richmond Hill,Ontario,L4c 9m7,Canada

Novartis Investigative Site

Recruiting

Waterloo,Ontario,N2j 1c4,Canada

Novartis Investigative Site

Recruiting

Sherbrooke,Quebec,J1l 0h8,Canada

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