Novartis Pipeline

Benefiting from our continued focus on innovation, Novartis has one of the industry’s most competitive pipelines. Many of these projects, which include new molecular entities as well as additional indications and different formulations for marketed products, are for medicines that could significantly advance treatment standards for patients worldwide. This table provides an overview of selected projects in development. Please note: the Novartis Pipeline data is updated quarterly.

Download the Novartis Pipeline from the 2024 Annual Report (PDF 0.1 MB)

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Showing 104 results
  • QMF149
    Atectura®
    Asthma, pediatrics
    In-market Brands and Global Health Phase 3 2027 LABA + ICS
  • RHH646
    RHH646
    Osteoarthritis
    Immunology Phase 2
    Lead Indication
  • RTH258
    Beovu®
    Diabetic retinopathy
    In-market Brands and Global Health Registration VEGF inhibitor
  • SEG101
    Adakveo®
    Sickle cell disease, pediatrics
    In-market Brands and Global Health Phase 3 ≥ 2028 P-selectin inhibitor
  • TIN816
    TIN816
    Acute kidney injury
    Cardiovascular, Renal and Metabolic Phase 2 ATP modulator
    Lead Indication
  • TQJ230
    pelacarsen
    Secondary prevention of cardiovascular events in patients with elevated levels of lipoprotein(a) (CVRR-Lp(a))
    Cardiovascular, Renal and Metabolic Phase 3 2026 ASO targeting Lp(a)
    Lead Indication
  • VAY736
    ianalumab
    Lupus Nephritis
    Immunology Phase 3 ≥ 2028 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VAY736
    ianalumab
    Systemic lupus erythematosus (SLE)
    Immunology Phase 3 ≥ 2028 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VAY736
    ianalumab
    Sjoegren's syndrome
    Immunology Phase 3 2026 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Lead Indication
  • VAY736
    ianalumab
    Systemic sclerosis
    Immunology Phase 2 ≥ 2028 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VAY736
    ianalumab
    1L Immune Thrombocytopenia
    Oncology: Hematology Phase 3 2027 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VAY736
    ianalumab
    2L Immune Thrombocytopenia
    Oncology: Hematology Phase 3 2027 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VAY736
    ianalumab
    warm Autoimmune Hemolytic Anemia
    Oncology: Hematology Phase 3 2027 BAFF-R inhibitor, ADCC-mediated B-cell depletor
    Supplementary Indication
  • VHB937
    VHB937
    Amyotrophic lateral sclerosis
    Neuroscience Phase 2 TREM2 stabilizer and activator
    Lead Indication
  • YMI024
    YMI024
    Inflammation-driven diseases
    Immunology Phase 1
    Lead Indication
  • YTB323
    rapcabtagene autoleucel
    Rheumatoid arthritis and severe, refractory Sjögren’s disease
    Immunology Phase 1 CD19 CART (CD19-targeted chimeric antigen receptor T-cell immunotherapy)
  • YTB323
    rapcabtagene autoleucel
    ANCA associated vasculitis
    Immunology Phase 2 ≥ 2028 CD19 CART (CD19-targeted chimeric antigen receptor T-cell immunotherapy)
    Supplementary Indication
  • YTB323
    rapcabtagene autoleucel
    srSLE/LN
    Immunology Phase 2 ≥ 2028 CD19 CART (CD19-targeted chimeric antigen receptor T-cell immunotherapy)
    Lead Indication
  • YTB323
    rapcabtagene autoleucel
    Myositis
    Immunology Phase 2 ≥ 2028 CD19 CART (CD19-targeted chimeric antigen receptor T-cell immunotherapy)
    Supplementary Indication
  • YTB323
    rapcabtagene autoleucel
    Systemic sclerosis
    Immunology Phase 2 ≥ 2028 CD19 CART (CD19-targeted chimeric antigen receptor T-cell immunotherapy)
    Supplementary Indication
Disclaimer

This information was factually accurate on the date it was published. Novartis assumes no duty to update the information to reflect subsequent developments. Readers should not rely upon the information on this page as current or accurate after its publication date. For the latest information on the Novartis' pipeline, readers should visit the News and Investors sections of our website. This information constitutes forward-looking statements relating to Novartis AG's business, including express or implied discussions regarding potential new products, potential new indications for existing products, or regarding potential future revenues from any such products. Such forward-looking statements reflect the current views of Novartis AG regarding future events, and involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from any future results, performance or achievements expressed or implied by such statements. There can be no guarantee that any new products will be approved for sale in any market, or that any new indications will be approved for existing products in any market, or that such products will achieve any particular revenue levels.

In particular, management's expectations could be affected by, among other things, uncertainties involved in the development of new pharmaceutical products; unexpected clinical trial results, including additional analysis of existing clinical data or unexpected new clinical data; unexpected regulatory actions or delays or government regulation generally; the Novartis Group's ability to obtain or maintain patent or other proprietary intellectual property protection, including the uncertainties involved in the US litigation process; competition in general; government, industry, and general public pricing and other political pressures; and other risks and factors referred to in Novartis AG's current Form 20-F on file with the US Securities and Exchange Commission. Should one or more of these risks or uncertainties materialize, or should underlying assumptions prove incorrect, actual results may vary materially from those described herein as anticipated, believed, estimated or expected.